Sugp1 surp and gpatch domain containing 1 longtailed. Gpatch domain and kow motifscontaining protein, gpkow. N metabolically labeled recombinant protein fragment. Probable component of an e3 ubiquitin protein ligase complex, in which it may act as a substrate. Sugp2 surp and gpatch domaincontaining protein 2 mus. The function of two helicases from this family, prp2 and prp43, is regulated by protein partners containing a gpatch domain. Mammalian splicing factor sf1 interacts with surp domains of. Sugp1 surp and g patch domain containing 1 is a protein coding gene. Loc111631469 surp and gpatch domaincontaining protein 1like bark scorpion gene id.
Protein analysis mass spectrometry protein expression protein interactions protein purification. Get started today with an existing dna file or order a selfdecode dna kit. Isoform 2 of trinucleotide repeatcontaining gene 6b protein 10342 tfg 0. Unbound material was incubated for 1 h at 4c with protein g. Surp and gpatch domaincontaining protein 2, serineargininerich splicing factor 14, splicing factor, arginineserinerich 14. Loc1162892 surp and gpatch domaincontaining protein 1like australian red waratah sea anemone gene id. Human dan26eprot, a multidomain protein, which, in addition to the g patch domain, contains an rna polymerase ii cterminal repeatbinding domain seen in many proteins of the polyaaddition machinery. Recently, it was reported that hotspot mutations in sf3b1 specifically disrupted the interaction with the spliceosomal protein, surp and the g patch domain containing 1 sugp1, without the interference of other sf3b1associated proteins. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. F23858 rbp rnabinding protein rbp sf4 splicing factor 4 surp and gpatch domaincontaining protein 1 product. Complete information for sugp1 gene protein coding, surp and gpatch domain containing 1, including. Ipr040169 surp and gpatch domaincontaining protein 12. Several groups of gpatch containing proteins are conserved in animals, plants.
The gpatch is a glycinerich domain discovered by sequence alignment, involved in protein protein and protein nucleic acid interaction. Sugp1 is a novel regulator of cholesterol metabolism human. Sugp2 surp and g patch domain containing 2 norway rat. Gpatch2 gene genecards gptc2 protein gptc2 antibody. The protein has been found to interact with several other proteins, including two from a splicing pathway.
Surp and gpatch domain containing 1 the function of sugp1. Sugp2 surp and gpatch domain containing 2 is a protein coding gene. Feature key positions description actions graphical view. Complete information for gpatch2l gene protein coding, gpatch domain containing 2 like, including. Sep 23, 2014 patatinlike phospholipase domain containing 3 gene. The g patch is a glycinerich domain discovered by sequence alignment, involved in protein protein and protein nucleic acid interaction.
Surp and gpatch domain containing 1 s homeolog sugp1. Figures and data in endothelial pka activity regulates. The function of two helicases from this family, prp2 and prp43, is regulated by protein partners containing a g patch domain. Ccdc75,coiledcoil domain containing protein 75, g patch domain containing protein 11,gpatch11,homo sapiens,human. Swap suppressorofwhiteapricotsurp domaincontaining protein d111gpatch domaincontaining protein at3g52120. Among these, 29 are associated with the u1 or u2 snrnps or. Surp and gpatch domaincontaining protein 1, rna binding protein rbp, splicing factor 4. G patch domain and ankyrin repeats 1 gpank1 protein profile protein summary this gene is located in a cluster of hlabassociated transcripts, which is included in the human major histocompatability complex iii region. Surp and g patch domain containing 1 sulf1 sulfatase 1 sulf2 sulfatase 2. Promotes the utilization of a cryptic splice site created by the beta110 mutation in the hbb gene. U2 small nuclear ribonucleoprotein a, putative, identical to u2 small nuclear ribonucleoprotein a. U5 small nuclear ribonucleoprotein helicase, putative. Sampson and hewitt 2003 also cloned the mouse orthologs.
Product title protein 29 conditioning hair groom tonic 4 oz average rating. Gpatch domain ipr000467 interpro entry interpro emblebi. Cub domain containing protein 1 cdh8 cadherin 8, type 2. Sugp1 surp and gpatch domain containing 1, authors. It is flanked by sugp1 a surp and g patch domain containing protein thought to play a role in premrna splicing and hapln4 a hyaluronan and proteoglycan link protein 4 that binds to hyaluronic acid and may be involved in formation of the extracellular matrix genes upstream and downstream respectively. Surp and g patch domain containing 2 supt7l suppressor of ty 7 s. Receptor g proteincoupled activity modifying protein 3.
Belongs to the upf0415 family 424 aa predicted functional partners. Mammalian splicing factor sf1 interacts with surp domains. Sfrs14 encodes a deduced 1,083amino acid protein with an estimated molecular mass of 120. Sf4 encodes a deduced 645amino acid protein with an estimated molecular mass of 72. Q9ui333 isoform 3 of sodium channel protein type 11 subunit alpha 22 0 1. Recombinant protein epitope signature tag prest antigen sequence. This is also the sequence that appears in the downloadable versions of the entry. Sugp1, previously known as splicing factor 4, has two tandem surp domains and a g patch domain. Surp and gpatch domaincontaining protein 1 gene id species. A scheme of surp domain containing proteins identified in y2h screens.
The gene has four transcript variants encoding two functional protein isoforms and is expressed in most human tissues. Omim is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers. After transcription, eukaryotic mrna precursors contain proteincoding exons. Loc111631469 surp and gpatch domaincontaining protein 1. Sugp2 surp and gpatch domaincontaining protein 2 homo. Help pages, faqs, uniprotkb manual, documents, news archive and biocuration projects. Gene ontology go annotations related to this gene include nucleic acid binding and rna binding. A complex component surp and gpatch domaincontaining protein 1 sugp1sf4.
All positional information in this entry refers to it. Browse our splicing factor 4 proteins antibodiesonline. Sugp1 surp and gpatch domaincontaining protein 1 homo. Pdf sugp1 is a novel regulator of cholesterol metabolism. Surp and gpatch domaincontaining protein 1 add blast. Gpatch2 g patch domaincontaining protein 2 homo sapiens. Rna analysis in vitro transcription nextgeneration sequencing rna. Mammalian splicing factor sf1 interacts with surp domains of u2.
Go annotations related to this gene include rna binding. Antisugp2 polyclonal antibody was developed using a human and is suitable for use in wb. Sugp2 surp and g patch domain containing 2 is a protein coding gene. At3g27600, swap suppressorofwhiteapricotsurp rnabinding domaincontaining protein. C20orf6,homo sapiens,human,sam domain containing protein 10,samd10,sterile alpha motif domain containing protein 10. Sugp1, surp and gpatch domain containing 1 orthology source. The resulting frameshift leads to sickle cell anemia. At3g27600, swap suppressorofwhiteapricotsurp rnabinding domain containing protein. Diseases associated with sugp1 include louping ill and osteogenesis imperfecta, type i.
Genomewide analysis of hepatic lipid content in extreme obesity. Diseases associated with gpatch2 include lymphogranuloma venereum and granuloma inguinale. Surp and g patch domain containing protein 2 sugt1 sugt1 sgt1 homolog, mis12 kinetochore complex assembly cochaperone sun1 sun1 sun domain containing protein 1. Two additional proteins containing surp domains were found by coip table 1, the u2 snrnpassociated surp motifcontaining protein u2surpsr140 and the a complex component surp and gpatch domaincontaining protein 1 sugp1sf4. Sugp1 surp and gpatch domaincontaining protein 1 mus. Human luca15, a multidomain rnabinding protein that is the product of a gene deleted in certain lung tumors. Gpatch11 is a protein that in humans is encoded by the gpatch domain containing protein 11 gene. Among its related pathways are mrna splicing major pathway. Surp and gpatch domaincontaining protein 2 oshomo sapiens gnsugp2.
Putative splicing factor, arginineserinerich 14, surp and gpatch domaincontaining protein 2, surp and gpatch domaincontaining protein 2. This isoform has been chosen as the canonical i sequence. Pdf gpatch domain and kow motifscontaining protein. Two additional proteins containing surp domains were found by coip table 1, the u2 snrnpassociated surp motif containing protein u2surpsr140 and the a complex component surp and g patch domain containing protein 1 sugp1sf4. The domain structure of sf3a120, cherp and sfswap is shown with surp domains indicated in dark grey. Buy products such as protein 29 conditioning hair groom clear gel, 3 oz. Sugp2, surp and gpatch domain containing 2 vertebrate orthologs 8 human ortholog sugp2, surp and gpatch domain containing 2. Capgly domain containing linker protein family, member 4. Surp and gpatch domaincontaining protein 1 recommended applications product description stable isotopelabeled standard for absolute protein quantification of sugp1. Sugp1 surp and gpatch domaincontaining protein 1 isoform. Pdf mammalian splicing factor sf1 interacts with surp. Sugp2 surp and gpatch domain containing 2 saffroncrested tyrantmanakin gene id. It is flanked by sugp1 a surp and gpatch domaincontaining protein thought to play a role in premrna splicing and hapln4 a hyaluronan and proteoglycan link protein 4 that binds to hyaluronic acid and may be involved in formation of the extracellular matrix genes upstream and downstream respectively. We also depleted 11 other select transcripts including some encoding sf3ab subunits, surpdomain andor gpatchdomaincontaining proteins, and two other control proteins, and in no case did we observe significant 3.
Among its related pathways are gene expression and mrna splicing major pathway. Pentatricopeptide repeat domaincontaining protein 3, mitochondrial. Gpatch2 gpatch domain containing 2 is a protein coding gene. Diseases associated with sugp1 include acquired immunodeficiency syndrome. Surp and gpatch domaincontaining protein 1, rnabinding protein rbp, splicing factor 4. Loc1162892 surp and gpatch domaincontaining protein 1. Human dan26eprot, a multidomain protein, which, in addition to the gpatch domain, contains an rna polymerase ii cterminal repeatbinding domain seen in many proteins of the polyaaddition machinery.
Sfrs14 also contains an arginineserinerich n terminus, suggesting that it is a novel member of the srrelated family of premrna processing factors. Rna helicases from the deahrha family are present in all the processes of rna metabolism. Diseasecausing mutations in sf3b1 alter splicing by. Protein name surp and gpatch domaincontaining protein 2 100% guarantee bethyl guarantees that its products will work under the same conditions stated on the product datasheet. Tm6sf2 is located on chromosome 19 precisely at locus 19p. Both sf4 and sfrs14 contain 2 surp motifs and a single gpatch domain in their c termini. Plays a role in the wnt signaling pathway, negatively regulating the expression of wnt signaling components ctnnb1 and hmga1. Splicing factor, arginineserinerich 14 sfrs14 aa 1010. Sugp2 surp and gpatch domain containing 2, authors. Gpatch2l gene genecards gpt2l protein gpt2l antibody.
Browse our g patch domain and ankyrin repeats 1 proteins. Qprest sugp1 mass spectrometry protein standard qprest31015. Sugp1 surp and gpatch domain containing 1 is a protein coding gene. Ijms free fulltext regulating divergent transcriptomes. Rho gtpase activating protein 29 arhgap35 rho gtpase activating protein 35. Omim entry 614396 gpatch domaincontaining protein 8.
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